可用于口腔软组织增量的聚乙烯醇和聚丙烯酰胺水凝胶的制备

›› 2016, Vol. 7 ›› Issue (3): 153-156.

可用于口腔软组织增量的聚乙烯醇和聚丙烯酰胺水凝胶的制备

邵丽梅¹,林云红²,张文云³,杨丽³,黄荣卫⁴

1. 成都军区昆明总医院
2. 昆明医科大学附属口腔医院修复科
3. 解放军昆明总医院口腔科
4. 昆明市儿童医院

收稿日期:2015-10-12 修回日期:2016-09-08 出版日期:2016-09-25 发布日期:2016-09-28
通讯作者: 林云红 E-mail:Email：LinYunhon@163.com

The preparation of polymer-polyvinyl alcohol (PVA) and polyacrylamide(PAM) hydrogel used for oral soft tissue increment

Received:2015-10-12 Revised:2016-09-08 Online:2016-09-25 Published:2016-09-28

摘要/Abstract

摘要： 目的：制备可用于口腔软组织增量的聚乙烯醇（polymer-polyvinyl alcohol (PVA)）、聚丙烯酰胺(polyacrylamide (PAM))水凝胶。方法：将经高温溶解、冷冻解冻法制备的PVA、PAM，用真空抽气干燥后制备成体积为18 mm×5mm×4mm、浓度分别为15wt%、20wt%、25wt%的干凝胶。将所制备的PVA和PAM干凝胶进行表征。结果：制备出的PVA质地较硬且均匀，表面光滑；PAM则脆性大且质地不均匀，可看到其中的孔隙，表面粗糙。结论：PVA、PAM在常温下搅拌可少量溶解于去离子水中，升高温度才可完全溶解。PVA经若干次冷冻解冻循环可交联成固态结构，经真空干燥后即可得到体积收缩2-3倍的干凝胶。

Abstract: Objective: To prepare polymer-polyvinyl alcohol(PVA)and polyacrylamide(PAM) hydrogel used for oral soft tissue expansion. Methods: PVA and PAM were dissolvedat a high temperature and frozen in a low temperature and then melted at room temperature. After being dried in the vacuum oven ,and cut into cubes which were 18 mm*5 mm*4 mm in volumewith the concentration of15wt%,20wt% and 25wt% respectively. The dry gel of PVA and PAM were characterized. Results: The dry gel of PVA was hard, homogeneous and smooth on the surface. But the dry gel of PAM could be found small holes on the surface and was fragile, uneven and rough. Conclusion: A small amount of PVA and PAM could be dissolved in deionized water through stirring at room temperature, but PVA and PAM could be completely dissolved at a higher temperature. PVA could be solidified through repeated freezing and unfreezing for several times, and become dry gel by vacuum drying , which woud be shrunken two or three times in the volume.

中图分类号:

R783.1

邵丽梅林云红张文云杨丽黄荣卫. 可用于口腔软组织增量的聚乙烯醇和聚丙烯酰胺水凝胶的制备[J]. , 2016, 7(3): 153-156.

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