Abstract: Abstract：Demineralized bone matrix (DBM) is a product which is created through demineralized, degreased and deproteinized of allograft or xenograft. DBM is mainly comprised of collagen and bone morphogenetic proteins (BMPs). It has satisfied biocompatibility and excellent three-dimensional space and can stimulate local undifferentiated mesenchymal cells to transform into osteoblasts or Chondroblasts, this is important for promoting the formation of bone and cartilage. This material has been used in clinical for the treatment of bone defects and shows good results. The purpose of this paper is to review the mechanism of the DBM in repairing bone defects, oral maxillofacial applications and to prospect the feasibility applications of DBM in dental pulp repair.