›› 2012, Vol. 3 ›› Issue (4): 197-200.

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The clinicopathologic observation of Kimura disease

  

  • Received:2012-09-10 Revised:2012-11-21 Online:2012-12-25 Published:2013-01-10

Abstract: 【Abstract】 Objective To improve the knowledge of the clinicopathologic features of Kimura disease(KD). Methods seven cases of Kimura disease were evaluated by light microscopy and immunohistochemistry. Results All the 7 cases were male, the age of onset were from 21 to 73 years. The typical clinical presentation was characterizde by painless subcutaeous and major salivary glands in the head and neck.The pathological characterisitics of KD were lymphoid tissue hyperplasia with prominent lymphoid follicles,enlargement of germinal center, conspicuous eosinophils infiltration and capillary proliferation. Immunohistochemical study in KD revealed B cells in the lymphoid follicles and mostly T cells in the interfollicular regions. Conclusions KD is an uncommon lymphoid tissue hyperplasia. It should be differentiated from tumor abundant with lymph tissue. The histopathologic diagnosis of KD is important.