›› 2014, Vol. 5 ›› Issue (4): 193-195.

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Expression of tight junction proteins in rat submandibular glands

  

  • Received:2014-07-22 Revised:2014-09-17 Online:2014-12-25 Published:2015-01-06

Abstract: Objective: To observe the expression of tight junction proteins in rat submandibular glands. Methods: The rat submandibular glands were isolated, frozen, and made into sections. Immunohistochemistry staining was used for observation. Results:Claudin-3 was expressed both in acinar and ductal cells. Claudin-4 was only expressed in ductal cells but not in acinar cells. Co-staining of claudin-4 with ZO-1, Claudin-3 with Occludin suggest that they are all distributed in tight junction. Conclusions:Tissue-specific expression of the tight junction proteins claudins was found in rat submandibular glands.