施万细胞来源的外泌体在骨代谢中的作用

Abstract

Abstract: Schwann cells (SCs) are an important type of peripheral nerve cell and studies have shown that peripheral nerve tissue cells such as SCs have an important regulatory role in bone tissue metabolism.By affecting Wnt, MAPK, Hippo and other signaling pathways, exosomes of Schwann cell origin may promote osteogenic differentiation of bone marrow stromal stem cells and others, and participate in the regulation of bone metabolic homeostasis in vivo. Focusing on the role of exosomes of Schwann cell origin in osteogenic differentiation and its mechanism may provide reference data and research directions for future studies on bone regeneration mechanisms, promotion of bone regeneration and exploration of new therapeutic means for jaw bone defect repair.

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Effect of exosomes from shwann cells under bone metabolism

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