牙源性角化囊性瘤开窗减压术后组织形态学改变

›› 2013, Vol. 4 ›› Issue (1): 40-43.

牙源性角化囊性瘤开窗减压术后组织形态学改变

王婧¹,武和明²,王丽珍³,张玮¹,丁旭⁴,邢树忠¹

1. 江苏省口腔医院口腔颌面外科
2. 南京医科大学附属口腔医院江苏省口腔医院口腔颌面外科
3. 上海市第九人民医院
4. 南京医科大学附属口腔医院

收稿日期:2012-11-23 修回日期:2013-03-08 出版日期:2013-03-25 发布日期:2013-03-30
通讯作者: 邢树忠 E-mail:xingshuzhong_ny@163.com

The postoperative histomorphological changes of keratocystic odontogenic tumor after decompression

Received:2012-11-23 Revised:2013-03-08 Online:2013-03-25 Published:2013-03-30

摘要/Abstract

摘要： 目的：探讨牙源性角化囊性瘤（keratocysitic odontogenic tumor，KCOT）开窗减压术后组织形态学的改变。方法：对比观察22例牙源性角化囊性瘤开窗减压术前及二期刮治术后组织学的改变，内容包括上皮形态、上皮及纤维层厚度、纤维层炎症浸润程度，并行统计学分析。结果：54.5%的病例开窗后上皮层不全角化消失同时出现钉突状增生；开窗后衬里上皮及纤维囊壁层明显增厚（P<0.05）；纤维层内炎症浸润程度显著加重（p<0.05）。结论：牙源性角化囊性瘤在开窗减压术后表现出衬里上皮及纤维囊壁显著增厚及纤维层内炎症细胞浸润加重的组织形态学特征，其具体机制及意义还需进一步研究。

Abstract: Objective：To investigate the histomorphological changes of the keratocystic odotogenic tumor after decompression. Methods：The histomorphologyical changes of 22 KCOT tissue slices stained with hematoxylin and eosin before decompression and after curettage were observed ，including the epithelial modality，the depth of the epithelium and connective tissue，the degree of inflammation infiltration adjective of the basal layer，then statistic analysis were made. Results：54.5 percent of the cases were found lost of epithelial para and localized hyperplasia with rete pegs, in addition, the thickness of both epithelium and connective layer increased statistically after decompression (P <0.05) and the degree of inflammation infiltration also intensified dramatically (P<0.05).Conclusions：The histomorphological features of KCOT have changed remarkably after decompression, appearing as the thickened linings and intensified inflammation infiltration, further research is needed to explain the mechanism of the above-mentioned changes.

中图分类号:

R739.82

王婧武和明王丽珍张玮丁旭邢树忠. 牙源性角化囊性瘤开窗减压术后组织形态学改变[J]. , 2013, 4(1): 40-43.

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