牙龈素在牙龈卟啉单胞菌生长及牙周致病过程中的作用

›› 2014, Vol. 5 ›› Issue (2): 99-101.

牙龈素在牙龈卟啉单胞菌生长及牙周致病过程中的作用

张瑞¹,孙卫斌²

1. 南京大学
2. 南京大学口腔医学院

收稿日期:2014-03-20 修回日期:2014-05-04 出版日期:2014-06-25 发布日期:2014-06-23
通讯作者: 孙卫斌 E-mail:wbsun@nju.edu.cn

The role of gingipains in the physiological process of Porphyromonas gingipain and pathogenesis of periodontal disease。

Rui ZHANG¹, ²

1. Nanjing University
2. Institute of Stomatology, Nanjing University

Received:2014-03-20 Revised:2014-05-04 Online:2014-06-25 Published:2014-06-23

摘要/Abstract

摘要： 牙龈素是慢性牙周炎的重要致病菌——牙龈卟啉单胞菌的最重要毒力因子。作为一组半胱氨酸蛋白酶，牙龈素能结合并降解多种宿主蛋白质。本文总结了目前对牙龈素的结构和功能的研究，主要从牙龈素对牙龈卟啉单胞菌生长代谢、对牙周组织的致病作用及宿主免疫的影响三个方面阐述。

张瑞孙卫斌. 牙龈素在牙龈卟啉单胞菌生长及牙周致病过程中的作用[J]. , 2014, 5(2): 99-101.

Rui ZHANG. The role of gingipains in the physiological process of Porphyromonas gingipain and pathogenesis of periodontal disease。[J]. , 2014, 5(2): 99-101.

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