›› 2016, Vol. 7 ›› Issue (2): 93-97.

• 综述 • 上一篇    下一篇

加速正畸牙移动方法及其分子机制的研究进展

朱琳琳1,李琥2,严斌3   

  1. 1. 南京医科大学口腔疾病研究江苏省重点实验室,南京医科大学附属口腔医院
    2. 南京医科大学附属口腔医院
    3. 江苏省口腔医院
  • 收稿日期:2016-04-07 修回日期:2016-05-23 出版日期:2016-06-25 发布日期:2016-06-22
  • 通讯作者: 严斌 E-mail:dentistyan@139.com
  • 基金资助:
    国家自然科学基金;江苏高校优势学科建设工程资助项目

Molecular mechanisms of different interventions for accelerating orthodontic tooth movement

Lin-lin ZHU1, 2, 3   

  1. 1. Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University;Affiliated Hospital of Stomatology, Nanjing Medical University
    2. Institute of Stomatology,Nanjing Medical University
    3.
  • Received:2016-04-07 Revised:2016-05-23 Online:2016-06-25 Published:2016-06-22

摘要: 摘要:如何在生理允许范围内加速牙齿移动、缩短治疗时间、降低龋坏、牙根吸收及牙周疾病等治疗风险,是绝大多数正畸医生都关心的问题。目前,加速牙齿移动的方法较多,大致可分为手术治疗、物理治疗、药物治疗和基因治疗四类。牙齿移动速度取决于牙周骨代谢速率,纵观目前的各类加速方法,均是通过作用于牙周骨代谢通路上的某一环节来加速牙齿移动。本文将对这些方法的分子机制进行综述。

Abstract: Abstract: Accelerating tooth movement, within the physiological range, can reduce the period of orthodontic treatment, thereby reducing the risks of caries, root resorption, periodontal diseases, etc. Currently, there are various modalities to accelerate tooth movement which can be categorized as follows: surgery, physiotherapy, drugs and gene therapy. The rate of tooth movement depends on the remodeling rate of tissues surrounding the roots. Throughout the clinical and experimental methods now in use, they all act on one of the links in periodontal bone remodeling. This review summarizes the molecular mechanisms of these methods.