›› 2017, Vol. 8 ›› Issue (4): 205-210.

• 论著 • 上一篇    下一篇

细胞谱系示踪技术及其在口腔医学研究中的应用进展

赵闫,欧阳宁娟,代杰文,沈国芳   

  1. 上海市第九人民医院
  • 收稿日期:2017-06-26 修回日期:2017-09-29 出版日期:2017-12-25 发布日期:2017-12-26
  • 通讯作者: 沈国芳 E-mail:maxillofacsurg@163.com
  • 基金资助:
    国家自然科学基金

Development of cell lineage tracing technology and its application in stomatology research

  • Received:2017-06-26 Revised:2017-09-29 Online:2017-12-25 Published:2017-12-26

摘要: 细胞谱系示踪技术对研究生物体生长发育、组织新陈代谢与疾病发生时各种细胞的起源、发生发展与转归十分重要,尤其在探索各种干细胞的谱系以及成熟细胞的前体来源细胞中应用广泛。细胞谱系示踪技术方法众多,且每一种技术都有其使用的范围、优势、原则和不足,本文就不同细胞示踪技术的发展与应用,尤其是在口腔医学研究中的应用,以及各自优势与不足进行综述。

Abstract: Cell lineage tracing technology plays an important role in studying the cell origin, proliferation and differentiation during the process of growth, metabolism, diseases development of organisms, especially for exploring the origin of different stem cells, as well as a variety of precursors of adult cells. There are various cell lineage tracing technologies, and every method exhibited different scope, principle, advantages and shortcomings. In this article, we would like to systematically review the development, application, advantages and disadvantages of different cell lineage tracing technologies, especially for application in the stomatology.