口腔生物医学 ›› 2022, Vol. 13 ›› Issue (2): 125-129.

• 综述 • 上一篇    下一篇

FAM83A在恶性肿瘤中的作用研究进展

徐佳妮1,李轩1,2,吉幻1,钟旖3   

  1. 1. 南京医科大学口腔疾病研究江苏省重点实验室
    2. 南京医科大学附属口腔医院口腔综合科
    3. 江苏省口腔医院病理科
  • 收稿日期:2021-04-13 修回日期:2022-05-11 出版日期:2022-06-25 发布日期:2022-07-07
  • 通讯作者: 钟旖 E-mail:236744209@qq.com
  • 基金资助:
    江苏省自然科学基金;江苏省卫健委医学科研项目

Research progress on FAM83A and its role in malignant tumors

  • Received:2021-04-13 Revised:2022-05-11 Online:2022-06-25 Published:2022-07-07

摘要: 序列相似性为83的家族成员A(FAM83A)在多种恶性肿瘤中均有表达,参与肿瘤的发生、发展和转移等过程,与临床预后密切相关,是一种潜在的肿瘤特异性抗原。本文对FAM83A的结构特点、在恶性肿瘤发生发展中的作用以及临床应用前景进行综述。

关键词: 序列相似性为83的家族成员A, 恶性肿瘤, 发生发展, 预后

Abstract: Family with sequence similarity 83 member A is widely expressed in various tumors and participates in the occurrence and development of human tumors. In recent years, FAM83A,closely related to clinical outcomes, has been proved to be a potential tumor-specific antigen, which plays a significant role in malignant tumors. In this paper, the structure of FAM83A, its role in malignant tumors and the potential prospects in clinical application were reviewed.

Key words: FAM83A, neoplasm, prognosis