微型种植体导致牙龈上皮异位植入的可能性初探

›› 2012, Vol. 3 ›› Issue (4): 178-180.

微型种植体导致牙龈上皮异位植入的可能性初探

张阳¹,李琥²,李强²,李媛²,张昊¹,倪媛媛¹,王林¹,马俊青¹

1. 南京医科大学
2. 南京医科大学附属口腔医院

收稿日期:2012-08-30 修回日期:2012-09-27 出版日期:2012-12-25 发布日期:2013-01-10
通讯作者: 马俊青 E-mail:junqingma2000@hotmail.com
基金资助:
国家自然科学基金;江苏省自然科学基金;江苏省高校优势学科建设工程资助项目

Primary study on the possibility of ectopically implanted epithelium caused by micro-implant

Received:2012-08-30 Revised:2012-09-27 Online:2012-12-25 Published:2013-01-10
Contact: Junqing Ma E-mail:junqingma2000@hotmail.com

摘要/Abstract

摘要： 目的：初步探讨微型种植体植入时携带牙龈上皮进入牙槽骨的可能性。方法：以比格犬为实验动物，在种植部位牙龈处注射含GFP的2型腺相关病毒（adeno-associated viral-2-green fluorescent protein，AAV2-GFP），0天处死动物，制作连续组织切片，通过GFP荧光和角化蛋白免疫组化检测种植体周围牙龈上皮是否存在。结果：两种检测方法均未发现种植体-骨界面有牙龈上皮的存在。结论：微型种植体植入时未发现携带牙龈上皮进入牙槽骨。

Abstract: Objective: To explore the possibility of ectopically implanted epithelium caused by micro-implant. Methods: Using Beagle dogs as experimental animal, AAV2-GFP were injected in the gingiva of implantation area. The dogs were euthanized at 0 d, and the bone specimen were made into serial slices. Fluorescences of cytokeratin antibody and GFP expressed by AAV2 were detected to demonstrate the ectopically implanted epithelium around the micro-implant. Results: Ectopically implanted gingivae epithelium wasn't found at the bone-implant interface by our two means of detection. Conclusions: No possibility of ectopically implanted epithelium caused by the placement of micro-implant was found.

中图分类号:

R780.2

张阳李琥李强李媛张昊倪媛媛王林马俊青. 微型种植体导致牙龈上皮异位植入的可能性初探[J]. , 2012, 3(4): 178-180.

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