关键词: 外泌体, 颌面组织再生, 牙髓再生, 牙周再生

Abstract: Exosomes are a kind of membrane vesicles that encapsulate proteins, RNAs and other substances selected and isolated in cells, which can regulate the biological reactions of distal cells and tissues through the circulatory system, and have a good application prospect in the regeneration of oral and maxillofacial tissues. This article reviews the new progress of exosomes in the field of oral and maxillofacial tissue regeneration engineering such as dental pulp, periodontium, bone, skin, and nerve, and summarizes the experience of oral and maxillofacial tissue regeneration and functional reconstruction based on the research of exosomes in recent years. The purpose of this article is to provide reference for research in this field and to look forward to the clinical translation and application prospect of exosome-based oral and maxillofacial tissue regeneration technology.

Key words: exosomes, regeneration of maxillofacial tissue, pulp regeneration, periodontal regeneration