口腔生物医学 ›› 2025, Vol. 16 ›› Issue (2): 117-120.

• 综述 • 上一篇    

妊娠期糖尿病及子痫前期的微生态变化

叶亭邑1,叶畅畅1,吴亚菲2   

  1. 1. 四川大学华西口腔医院
    2. 口腔疾病防治全国重点实验室,国家口腔医学中心,国家口腔疾病临床医学研究中心,四川大学华西口腔医院牙周病科
  • 收稿日期:2024-07-10 修回日期:2024-11-27 出版日期:2025-04-25 发布日期:2025-05-08
  • 通讯作者: 吴亚菲 E-mail:yfw1110@163.com

Oral microecology and pregnancy complications

  • Received:2024-07-10 Revised:2024-11-27 Online:2025-04-25 Published:2025-05-08

摘要: 微生态的平衡具有重大意义,其失衡与全身各种疾病的发生息息相关。妊娠期的孕妇会发生相应的变化,例如体重增加、雌激素和孕酮上涨、同时伴有免疫系统的改变等,从而导致人体微生态发生一系列变化。菌群与宿主免疫系统的共同作用会导致疾病的发生发展,可能与一系列的妊娠期并发症有关,包括妊娠期糖尿病、子痫前期等。本文结合近年研究阐述妊娠并发症与微生态之间的关系,妊娠期并发症与孕妇口腔、肠道、阴道微生态的变化相关性。

关键词: 牙周炎, 微生态, 妊娠期糖尿病, 子痫前期

Abstract: The balance of microecology is of great significance, and its imbalance is closely related to the occurrence of various diseases in the whole body. During pregnancy, pregnant women will undergo corresponding changes, such as weight gain, estrogen and progesterone increase, accompanied by changes in the immune system, resulting in a series of changes in the human microecology. The interaction between the flora and the host immune system can lead to the development of disease and may be associated with a range of pregnancy complications, including gestational diabetes and preeclampsia. This paper discusses the relationship between pregnancy complications and microecology based on recent studies, and the correlation between pregnancy complications and changes in oral, intestinal and vaginal microecology of pregnant women.

Key words: Periodontitis , Micro-ecology , Gestational Diabetes, Preeclampsia