十二烷基磺酸钠清除根管内Vitapex糊剂的实验研究

摘要/Abstract

摘要： 目的：研究十二烷基磺酸钠（SDSn）溶液对根管内Vitapex糊剂的清除效率。方法：通过X线目的：研究十二烷基磺酸钠（SDSn）溶液对根管内Vitapex糊剂的清除效率。方法：通过X线片计算根管冲洗前后Vitapex糊剂面积，比较不同冲洗方案下根管内Vitapex糊剂的清除率。选用直根管模块，筛选出SDSn清除根管内Vitapex糊剂最佳浓度；比较蒸馏水、1% NaClO、17% EDTA、7%马来酸（MA）、10%柠檬酸（CA）、1% SDSn等液体对直根管内Vitapex糊剂的清除效率；比较1% NaClO+H锉（HF）、1% NaClO+Gentlefile Brush（GF）、1% SDSn+HF、1% SDSn+GF等不同器械联合溶液对直根管内Vitapex糊剂的清除效率。选用25°弯曲根管模块，比较1% NaClO+双向开口冲洗针、1% NaClO+IrriFlex冲洗针、1% SDSn+双向开口冲洗针、1% SDSn+IrriFlex冲洗针等不同冲洗针联合溶液对弯根管内Vitapex糊剂的清除效率。结果：1% SDSn对根管内Vitapex糊剂清除率高于0.1% SDSn（P＜0.05），与5%SDSn和10%SDSn比较无显著差别（P＞0.05）；1% SDSn对根管内Vitapex糊剂清除率均高于1% NaClO、17% EDTA、7% MA、10% CA（P＜0.05）；在直根管，Gentlefile Brush的使用显著提高了1% NaClO组的清除率（P＜0.05），而并未显著提高1% SDSn组的清除率（P＞0.05）；在弯曲根管中下段，1% SDSn+IrriFlex冲洗针的清除率显著高于1% SDSn+双向开口针头（P＜0.05）。结论：1% SDSn对根管内Vitapex糊剂有较好的清除效果；对于直根管，使用1% SDSn联合Gentlefile Brush能提高Vitapex糊剂的清除率；对于弯曲根管中下段，使用1% SDSn联合IrriFlex冲洗针头能有效提高Vitapex糊剂的清除率。

关键词: 根管冲洗, Vitapex糊剂, 十二烷基磺酸钠, 根管内药物, 弯曲根管

Abstract: Objective:?To investigate the clearance of SDSn solution on Vitapexpaste. Methods:?The area of Vitapex paste in the root canal before and after irrigation was calculated by X-ray films, and the clearance rate of Vitapex paste in the root canal under different irrigation schemes was compared. Straight root canal modules were selected,and the optimal concentration of SDSn for removing Vitapex paste in the root canal was screened out. The clearance efficiency of Vitapex paste in straight root canals by distilled water, 1% NaClO, 17% EDTA, 7% maleic acid (MA), 10% citric acid (CA), and 1% SDSn was compared. The clearance efficiency of Vitapex paste in straight root canals by different instruments combined with solutions such as 1% NaClO + H-file (HF), 1% NaClO+ Gentlefile Brush (GF), 1% SDSn + HF, and 1% SDSn + GF was compared. 25° curved root canal modules were selected, and the clearance efficiency of Vitapex paste in curved root canals by different irrigation needles combined with solutions such as 1% NaClO+ double-ended irrigation needle, 1% NaClO + IrriFlex irrigation needle, 1% SDSn + double-lumen flushing needle, and 1% SDSn + IrriFlex irrigation needle was compared. Results:?The clearance rate of Vitapexin 1% SDSn groupwas higher than that of 0.1% SDSn group (P＜0.05), but there was no significant difference compared with 5% SDSn groupand 10% SDSn group (P＞0.05). The clearance rate of Vitapex by 1% SDSn group was higher than that of 1% NaClO group, 17% EDTA group, 7% MA group, and 10% CA group (P＜0.05). In straight root canals, the use of Gentlefile Brush significantly increased the clearance rate in 1% NaClO + GF group (P＜0.05), but did not significantly increase the clearance rate in 1% SDSn + GFgroup (P＞0.05). In the middle and lower segments of curved root canals, 1% SDSn + IrriFlex needle group significantly increased the clearance rate compared with 1% SDSn + double-lumen flushing needle group (P＜0.05). Conclusions: 1% SDSn is efficient in removing Vitapex paste from root canals. For straight root canals, the combination of 1% SDSn and Gentlefile Brush can increase the clearance rate of Vitapex paste. For the middle and lower sections of curved root canals, the use of 1% SDSn in conjunction with the IrriFlex irrigation needle can effectively enhance the clearance rate of Vitapex paste.

Key words: root canal irrigation, vitapex paste, sodium dodecyl sulfonate, intracanal medication, curved root canals

郁皓文李娜吴锦涛李泽汉闫明于金华. 十二烷基磺酸钠清除根管内Vitapex糊剂的实验研究[J]. 口腔生物医学, 2025, 16(3): 135-140.

参考文献 27

[1]	Mohammadi, Z. and P.M. Dummer. Properties and applications of calcium hydroxide in endodontics and dental traumatology[J]. Int Endod J, 2011, 44(8): 697-730
[2]	Arag?o, A.C., et al. Root canal obturation materials and filling techniques for primary teeth: In vitro evaluation in polymer-based prototyped incisors[J]. Int J Paediatr Dent, 2020, 30(3): 381-389
[3]	Weng, Q.F. [Clinical study on the effect of Vitapex paste in apexification][J]. Hua Xi Kou Qiang Yi Xue Za Zhi, 2004, 22(3): 214-5
[4]	Al Khasawnah, Q., et al. Nonsurgical Clinical Management of Periapical Lesions Using Calcium Hydroxide-Iodoform-Silicon-Oil Paste[J]. Biomed Res Int, 2018, 2018: 8198795
[5]	Ghosh, S., et al. Comparative evaluation of different forms of calcium hydroxide in apexification[J]. Contemp Clin Dent, 2014, 5(1): 6-12
[6]	Kwon, W., et al. Comparative study of pulpal responses to ProRoot MTA, Vitapex, and Metapex in canine teeth[J]. J Dent Sci, 2021, 16(4): 1274-1280
[7]	Porkaew, P., et al. Effects of calcium hydroxide paste as an intracanal medicament on apical seal[J]. J Endod, 1990, 16(8): 369-74
[8]	Nainan, M.T., D. Nirupama, and S. Benjamin. Comparison of the efficacy of ethylene diamine tetraacetic acid and maleic acid in the removal of three calcium hydroxide intra-canal dressings: A spiral computerized tomography volumetric analysis[J]. J Conserv Dent, 2013, 16(1): 56-60
[9]	Shakapuram, G., et al. Efficacy of passive ultrasonic irrigation in the removal of three different intracanal medicaments - An in-vitro study[J]. Indian J Dent Res, 2021, 32(3): 390-394
[10]	Guiotti, F.A., et al. Effect of calcium hydroxide dressing on push-out bond strength of endodontic sealers to root canal dentin[J]. Braz Oral Res, 2014, 28
[11]	Calt, S. and A. Serper. Dentinal tubule penetration of root canal sealers after root canal dressing with calcium hydroxide[J]. J Endod, 1999, 25(6): 431-3
[12]	Hosoya, N., et al. Effects of calcium hydroxide on physical and sealing properties of canal sealers[J]. Int Endod J, 2004, 37(3): 178-84
[13]	Kim, S.K. and Y.O. Kim. Influence of calcium hydroxide intracanal medication on apical seal[J]. Int Endod J, 2002, 35(7): 623-8
[14]	周立国, 段洪东, 刘伟, 精细化学品化学[M]. 化学工业出版社, 2021:13-16
[15]	Cheng, Y. and S. Yuan. Emulsification of Surfactant on Oil Droplets by Molecular Dynamics Simulation[J]. Molecules, 2020, 25(13)
[16]	Kumar, P., et al. A cone-beam computed tomography assessment of the efficacy of different irrigation devices for removal of silicone oil-based calcium hydroxide from root canal system[J]. J Conserv Dent, 2017, 20(2): 68-71
[17]	Chandran, A., et al. Comparison of the Efficacy of K-File, Canal Brush Technique, and Sonic Irrigation Technique in the Retrievability of Calcium Hydroxide and Metapex Intracanal Medicaments from Root Canals: An In vitro Cone-Beam Computed Tomography Analysis[J]. J Pharm Bioallied Sci, 2021, 13(Suppl 1): S496-s500
[18]	Xu, X., et al. Effect of conventional needle irrigation, passive ultrasonic irrigation, sonic irrigation and XP-endo finisher in removing intracanal Vitapex paste[J]. Aust Endod J, 2023, 49 Suppl 1: 374-380
[19]	Bajaj, H., et al. Comparative evaluation of removal of oil-based calcium hydroxide intracanal medicaments with two calcium chelators: An in vitro cone-beam computed tomography volumetric analysis[J]. J Conserv Dent Endod, 2024, 27(11): 1163-1167
[20]	Ballal, N., et al. Susceptibility of Candida albicans and Enterococcus faecalis to Chitosan, Chlorhexidine gluconate and their combination in vitro[J]. Aust Endod J, 2009, 35(1): 29-33
[21]	Yoo, Y.J., et al. Efficacy of Different Irrigation Needles and Ultrasonic Activation on Calcium Hydroxide Removal: A Micro-CT Study Using 3D-Printed Endodontic Models[J]. J Endod, 2024, 50(10): 1478-1483
[22]	Htun, P.H., et al. Cleaning and Shaping Ability of Gentlefile, HyFlex EDM, and ProTaper Next Instruments: A Combined Micro-computed Tomographic and Scanning Electron Microscopic Study[J]. J Endod, 2020, 46(7): 973-979
[23]	Pawar, O., et al. Effect of Finisher Gentlefile brush, XP-endo Finisher and ultrasonic irrigation for the removal of calcium hydroxide paste from root canal[J]. Bioinformation, 2024, 20(9): 1052-1058
[24]	Song, Y., et al. Calcium hydroxide removal in curved root canals with apical transportation In Vitro[J]. J Huazhong Univ Sci Technolog Med Sci, 2014, 34(4): 608-611
[25]	Baasch, A., et al. Influence of irrigation needle design on cleaning efficiency in 3D mandibular molar models[J]. Odontology, 2025
[26]	Habeeb, M.A. Comparative evaluation of debris and irrigation extruded apically using different design of needles and penetration depth - An In Vitro study[J]. Indian J Dent Res, 2023, 34(3): 266-269
[27]	Provoost, C., et al. Influence of Needle Design and Irrigant Flow Rate on the Removal of Enterococcus faecalis Biofilms In Vitro[J]. Dent J (Basel), 2022, 10(4)