›› 2013, Vol. 4 ›› Issue (3): 145-150.

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Research on the effects of different micro-environments on the biology of dental pulp stem cells

  

  • Received:2013-05-28 Revised:2013-07-17 Online:2013-09-25 Published:2013-10-22

Abstract: Dental pulp stem cells (DPSCs) are one type of adult stem cells with the potential of self-renewing and multi-differentiation, which are considered as a competent candidate for tooth/bone tissue regeneration. The biological features especially the odonto/osteogenic capacity of DPSCs can be affected by different conditions which subsequently compromises their applications in tissue engineering. Thus, the selection of an ideal microenvironment for DPSCs is much important to the better use of DPSCs in tissue regeneration. This review will mainly focus on the effects of different factors, such as cytokines, conditioned media, scaffold materials, and physical elements on the biology of DPSCs.