›› 2014, Vol. 5 ›› Issue (2): 95-98.

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Runx2 expression in tooth development

  

  1. 1. School of Stomatology, Nanjing Medical University
    2.
  • Received:2014-03-25 Revised:2014-05-12 Online:2014-06-25 Published:2014-06-23

Abstract: Runt-related transcription factor 2(Runx2) is a transcription factor that plays an important role in osteoblast differentiation and tooth development, which regulates the expression of specific matrix proteins of teeth and bone at transcriptional level. Considering the characteristics of Runx2 and its expression during tooth development, it is speculated that Runx2 play important role in tooth development and mineralization.