Abstract: Congenital cleft lip and palate(CLP)is the most common one of the birth defects, which has a serious impact on the oral function,facial morphology and mental health.It is a constant pursuit of scholars to restore the aesthetic and functional defects in patients with CLP.Clinically,Operaters should make surgery programs and predict postoperative facial morphology based on accurate quantitative measurement of maxillofacial area.Commonly used two-dimensional measurements are photo measurement and X-ray measurement,both are simple to operate and practical,low cost,but not accurate enough.Three-dimensional measurements such as computer tomography, stereoscopic photography,laser scanning can analyze the facial shape objectively and quantitatively,These three-dimensional measurements have broad application prospects with high accuracy,efficiency and convenience.Moreover,With the development of dynamic three-dimensional imaging technology,the dynamic 3D image capture technology is applied in dynamic analysis of maxillofacial region,and is expected to play an important role in the measurement of patients with CLP.