Abstract: [Abstract] Objective: The aim of this study was to compare the efficacy of different irrigation techniques on the removal of intracanal medicaments.Methods: 90 extrated single-rooted premolars were decoronated to obtain a standardized root length of 13 mm.The roots were split longitudinally into two halves and an artificial groove was prepared in the apical part of one segment.The triple antibiotic paste and calcium hydroxide were placed into the grooves.Two weeks later,the root canals were then irrigated with 10ml 1% NaOCl by three irrigation techiniques（ conventional syringe irrigation ,vibringe sonic irrigation and passive ultrasonic irrigation）.The amounts of intrcanal medicaments remaining in the grooves were scored with a stereomicroscope ,and the data were evaluated statistically.Results:Vibringe sonic irrigation and passive ultrasonic irrigation with 1% NaOCl removed significantly more triple antibiotic paste than the syringe irrigation(p<0.01).The syringe irrigation was associated with significantly more remaining calcium hydroxide than passive ultrasonic irrigation(p<0.01). There were no significant differences between vibringe sonic irrigation and the other two methods(vibringe sonic irrigation and syringe irrigation) on removing the calcium hydroxide.The groups of two medicaments with the same irrigation technique did not have significant differences.Conclusions:All the irrigation techniques cannot completely remove the intracanal medicaments.The use of vibringe sonic root canal irrigator and ultrasonic system may improve the efficacy of irrigation on the removal of intracanal medicaments.