›› 2020, Vol. 11 ›› Issue (4): 262-264.

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Research progress of gene SNRNP200

Xiaomin -Su1,   

  • Received:2020-07-27 Revised:2020-10-27 Online:2020-12-25 Published:2020-12-31

Abstract: SNRP200 is the splicing gene of nuclear precursor mRNA, and the encoded protein belongs to DEXH-box protein family of RNA helicase, which is widely expressed in the whole body tissues. In recent years, studies have shown that SNRNP200 is closely related to the splicing of precursor mRNA, and it can regulate the expression of related genes by influencing splicing, thus affecting cell proliferation. In addition, SNRNP200 also plays an important role in the pathogenesis of hereditary retinitis pigmentosa and acute myeloid leukemia (AML). In this paper, the structural characteristics, functional regulation and effects on diseases of SNRNP200 were reviewed.

Key words: SNRNP200, Pre-mRNA , Splice