Abstract: Objective：To evaluate the clinical effects of pulp revascularization of the immature permanent teeth with periapical lesions or pulp necrosis caused by the trauma or the dens evaginatus. Another purpose of the present study was to investigate the factors which may affect the treatment. Methods:66 cases of periapical lesions or pulp necrosis in immature permanent teeth were collected and treated by pulp revascularization. Mimics software was used to reconstruct a three-dimensional model of the periapical lesion before and after the treatment of the affected tooth. Then the volume of the apical lesions were measured. Dolphin software was used to measure the root length, the thickness of the root canal wall and apical foramen size before and after the treatment of the affected teeth. And to evaluate the factors which may affect the treatment. Results:According to the efficacy assessment criteria, 40 teeth were evaluated as "cured" (60.6%), 24 teeth as "improved" (36.4%), and two teeth as "ineffective" (3%). The preoperative inflammatory status significantly affected the root development (P<0.05). Conclusions:Pulp revascularization effectively promoted the healing of periapical lesions and achieved continuous root development. The preoperative inflammatory status can affect the root development.

Key words: pulp revascularization, immature permanent teeth, Clinical evaluation