牙龈卟啉单胞菌感染影响宿主DNA损伤修复机制的研究进展

Abstract

Abstract: Porphyromonas gingivalis （P. gingivalis） is a key pathogen in periodontal infections, with various pathogenic mechanisms such as activation of inflammatory responses, internalization of host cells to evade immune clearance, and reshaping of host cell biological behaviors. As research into microbial infections progresses, increasing evidence suggests that microbial infection is closely related to DNA damage of the host cell genome. This article aims to discuss research progress on how P. gingivalis affects DNA damage and repair capabilities of host cells from the perspective of its main pathogenicity, providing new insights for exploring the deeper pathogenic mechanisms of P. gingivalis.

CLC Number:

R781.4+2

References

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Research progress on effect of Porphyromonas gingivalis infection on host DNA damage and repair mechanisms

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