Abstract: Objective：To explore the application of computer-aided dynamic navigation system in zygomatic implantation. Methods：A 48-year-old male with severely atrophicmaxilla was selected and then two bilateral zygomatic implants were implanted with computer-aided dynamic navigation system according to the angulation of anterior teeth. The final restoration was completed six months after the implantation.Results：The patient achieved good therapeutic effect and his masticatory function recovered well. After three years of observation, no obvious bone resorption was found in both implants, and the patient was satisfied with the therapeutic effect. Conclusions：Computer-aided dynamic navigation system enjoys bright application prospects since it can effectively avoid the risk of zygomatic implant.