Abstract: Objective: To evaluate the clinical efficacy of variation design of the upper margin of cingulum in all-ceramic crown restoration for upper anterior teeth in deep over-bite patients. Methods: 60 anterior teeth from 36 deep overbite patients were restored with zirconia all-ceramic restorations (upper margin of lingual cingulum). The restorations were evaluated 6 months later according to the Modified USPHS Criteria. Results: 96.67% of 60 restorations were scored A in indices like crown integrity , margin sealing, margin coloring,color, shape, secondary caries, and gingival 6 months later. Conclusions: The variation design of the upper margin of cingulum provides clinically effective method in all-ceramic crown restoration for upper anterior teeth in deep overbite patients.