长链非编码RNA对间充质干细胞定向分化调控作用的研究进展

摘要/Abstract

摘要： 长链非编码RNA（LncRNA）参与多种细胞分化与发育，在X染色体失活、肿瘤、免疫系统、神经系统和心血管系统疾病等多种生物学过程和疾病的调控起着重要的作用。然而，关于lncRNA在间充质干细胞的生物发生和分化中的关键作用及机制探讨较少。本文就lncRNA在调节间充质干细胞中的作用，包括脂肪分化、成肌分化、成血管分化和成神经分化等细胞分化进行了综述，并探讨了lncRNA作为疾病治疗靶点的的潜在应用价值。

刘惠娜范志朋. 长链非编码RNA对间充质干细胞定向分化调控作用的研究进展[J]. , 2019, 10(2): 92-96.

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长链非编码RNA对间充质干细胞定向分化调控作用的研究进展

An overview of long non-coding RNA involved in directional differentiation of mesenchymal stem cells

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