γδ T细胞的抗肿瘤作用机制及免疫治疗前景

摘要/Abstract

摘要： 与传统的αβ T细胞不同，γδ T细胞不依赖主要组织相容性复合物（MHC）介导抗原识别，因此在癌症免疫治疗中具有巨大的应用潜力。本文就γδ T细胞的主要亚群及其在肿瘤微环境中的作用机制、免疫治疗策略进行综述，指出临床应用中需考虑的挑战和未来研究方向，为口腔鳞癌等肿瘤的免疫治疗提供新的思路。

马艺宁刘晓程雪乔春燕. γδ T细胞的抗肿瘤作用机制及免疫治疗前景[J]. 口腔生物医学, 2025, 16(1): 48-52.

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γδ T细胞的抗肿瘤作用机制及免疫治疗前景

Anti-tumour mechanism of action of γδ T cells and prospects for immunotherapy

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