Bmal1基因对牙体硬组织生长发育影响的研究进展

摘要/Abstract

摘要： Bmal1是生物钟基因的核心基因，通过负反馈调节主导其他生物钟基因的表达和翻译。牙体硬组织的发育是一系列复杂的生理过程，包括牙釉质、牙本质和牙骨质基质的形成和矿化。Bmal1基因作为生物节律的核心基因，对牙体硬组织的生长发育有重要影响，本文对Bmal1基因对牙体硬组织生长发育的影响进行综述。

关键词: Bmal1基因, 昼夜节律, 牙釉质, 牙本质, 牙骨质

Abstract: Bmal1 is the core gene of biological clock genes, which dominates the expression and translation of other biological clock genes through negative feedback regulation. The development of dental hard tissue is a series of complex physiological processes, including the formation and mineralization of enamel, dentin and cementum matrix. Bmal1 gene, as the core gene of biological rhythm, has an important effect on the development of dental hard tissue. This paper reviews the research progress of the effect of Bmal1 gene on the growth and development of dental hard tissue.

Key words: Bmal1 gene, circadian rhythm, enamel, dentin, cementum

刘莹陈阳彭淑桢王敏夏海斌. Bmal1基因对牙体硬组织生长发育影响的研究进展[J]. 口腔生物医学, 2022, 13(3): 195-202.

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