颌骨与不同部位来源骨髓间充质干细胞应用潜能的比较

口腔生物医学 ›› 2023, Vol. 14 ›› Issue (1): 46-49.

颌骨与不同部位来源骨髓间充质干细胞应用潜能的比较

俞悦¹,吴佳益¹,汪成林¹,叶玲¹,^2*

1. 口腔疾病研究国家重点实验室，国家口腔疾病临床医学研究中心，四川大学华西口腔医院牙体牙髓病科
2. 四川大学华西口腔医院，口腔疾病研究国家重点实验室

收稿日期:2022-12-14 修回日期:2023-01-14 出版日期:2023-03-25 发布日期:2023-03-29
通讯作者: 叶玲 E-mail:yeling@scu.edu.cn
基金资助:
颌骨缺损修复组织工程的合作研究

Comparation of the potential application of bone marrow mesenchymal stem cells from jaws and other regions.

1. Hospital of Stomatology Sichuan University
2.
3. 1

Received:2022-12-14 Revised:2023-01-14 Online:2023-03-25 Published:2023-03-29
Contact: Ling Ye E-mail:yeling@scu.edu.cn

摘要/Abstract

摘要： 骨髓间充质干细胞（BMSCs）的骨组织工程技术是目前治疗骨缺损的前沿方法。目前BMSCs的研究多聚焦于躯干骨（如髂骨）和附肢骨（如长骨）来源的BMSCs，而大量研究显示颅颌面骨（如颌骨）来源的BMSCs相较于其他部位来源的BMSCs在表型和功能上存在差异。本文对颌骨与其他部位来源BMSCs的比较研究做一综述，从而推测颌骨来源的BMSCs具有更强的应用潜能，更适合作为骨组织工程（尤其是颅颌面骨缺损修复）的种子细胞。

Abstract: Bone Marrow Stromal Cells (BMSCs) are a kind of multifunctional stem cells with multi-directional differentiation potential. BMSCs-based bone tissue engineering technology is currently a new method for the treatment of bone defects. Nowadays, the studies on BMSCs mainly focused on those isolated from bones of trunk and appendicular skeleton. However, many comparative studies showed that BMSCs from the craniofacial skeleton display specificities in phenotype and function. Therefore, jaw bone BMSCs may be more suitable for bone tissue engineering technology.

俞悦吴佳益汪成林叶玲. 颌骨与不同部位来源骨髓间充质干细胞应用潜能的比较[J]. 口腔生物医学, 2023, 14(1): 46-49.

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