Abstract: Objective: To establish the digital slides database for oral histopathology teaching. Methods: Using Nano Zoomer 2.0-HT system scanned classic oral histopathology slides. Results: Seventy-eight slides have been scanned, including 10 pieces of grinding slides and 68 pieces of soft tissue slides. Conclusions: The teaching digital slides database may promote the oral histopathology teaching reform and accelerate the process of informatization.