lncRNA调控牙周炎组织中PDLSCs生物学行为的研究进展

Abstract

Abstract: In recent years, several studies have shown that long non-coding RNA (lncRNA) plays crucial roles at multiple levels, such as epigenetic level, transcriptional and post-transcriptional levels. lncRNA is extensively involved in the biological behavior of PDLSCs, including proliferation, inflammatory immune response, and multidirectional differentiation. A great number of lncRNAs are significantly differentially expressed in healthy periodontal tissues and tissues affected by periodontitis, and the differential expression of lncRNAs is closely related to the abnormal biological behavior of PDLSCs. This paper reviews the mechanisms by which lncRNA regulates the biological behavior of PDLSCs affected by periodontitis.

Key words: lncRNA, periodontitis, periodontal ligament stem cell

References 50

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Progress in studies on lncRNA mediates the biological behavior of periodontal ligament stem cells in periodontitis tissues

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